Surface modification of PMMA IOLs by the immobilization of hydroxyethyl methacrylate for improving the biocompatibility
نویسندگان
چکیده
To improve biocompatibility of hydrophobic polymethyl methacrylate intraocular lens (PMMA IOL), 2-hydroxyethyl methacrylate (HEMA) was immobilized by UV-induced graft copolymerization method. The hydrophilicity and chemical composition of the PMMA IOL surface after each step of surfaces modification were analyzed by contact angle (CA) and X-ray photoelectron spectroscopy (XPS). The morphology of the IOL surface was characterized by atomic force microscopy (AFM). The results revealed that the hydrophilicity of the HEMA-g-PMMA IOL samples were significantly and permanently improved. The surface biocompatibility of the modified IOL was evaluated by platelets adhesion experiments.
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